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Thus, non-competitive agonists that blockade the NMDA receptor, such as ketamine or phencyclidine (PCP), have been increasingly used in animal models of schizophrenia and have been shown to induce hyperlocomotion, social withdrawal, and impairment of both cognition and pre-pulse inhibition in rodents [100]
This work was financially supported by the National Natural Science Foundation of China (32400218), the International Science and Technology Cooperation Project of Henan Province (252102520065), the Key Technology R&D Program of Henan Province (242102110240, 232102110053), the Special Support Fund for High-level Talents and skills improvement of Henan Agricultural University (30501474)
