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The loose skin under their eyes is typical for smokers, according to Bahman Guyuron, MD, of Case Western Reserve University

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Depending on the severity of the outbreak, there are convenient antiviral treatments available to control symptoms and speed up recovery time

Key Point: Heavy smokers often require higher-dose patches initially, followed by gradual tapering

But in this case, none of the available tools are perfect

This is manifested by increased mitochondrial mass, fusion, and leaky mitochondrial membranes, phenomena that result from an impaired autophagic mechanism that scavenges damaged mitochondria (i.e., mitochondrial autophagy) (85)