Other factors include, but are not limited to: 1 Age nicotine clearance decreases with age Sex studies have found women metabolize nicotine and cotinine faster than men Estrogen hormones there is a strong relationship between high estrogen levels, observed in premenopausal women, and increased metabolism of nicotine Smoking tobacco itself can also impact how long nicotine stays in your system
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genetic liability), or it might mean there is a gateway effect thats limited to experimentation or trial of cigarettes (but no evidence that theres an effect for current smoking, which is the thing we should care about)
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So we would draw very heavily on their advice and their experience in that respect,"