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Quality assessment Quality assessment of individual studies was completed independently by two reviewers, and any disagreements were resolved by discussion between the reviewers

S2CID 23066882

Practitioners should inform patients of the current knowledge gap and that the full effect of e-cigarettes is still to be investigated

A 2023 study of the California Tobacco Control Program found that the program prevented the consumption of nearly 16 billion packs of cigarettes from 1989 to 2019, and that spending one more dollar per capita reduced average consumption of cigarettes per adult current smoker by about two packs a year

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(7) In addition, nicotine decreases connective tissue turnover