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Let's get this straight smoking messes with your brain chemistry

Per The Cleveland Clinic, misophonia is a disorder that's characterized by "a decreased tolerance to specific sounds and things you can sense related to them." Misophonia isn't officially recognized as a "distinct disorder," but is widely recognized by experts

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The M2b subset most accurately reflects the intermediate phase between M1 and M2 with the release of both pro- and anti-inflammatory cytokines including IL-10, IL-1, IL-6 and TNF- which promote a Th2 response as well as tissue remodeling