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Fu (University of Toronto) for assistance with Figs 13

Light incidents can be neutralized within a turnover if you act quickly, but residues from repeated or chronic smoking can persist for months or longer without source removal.

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Discoloration or degradation of the material (especially in vulcanite or acrylic stems)

6 In a meta-analysis of randomized trials and observational studies comparing rhythm with rate control, management strategies were comparable with respect to all-cause (OR, 1.34 [95% CI, 0.89-2.02]) and cardiac mortality (OR, 0.96 [95% CI, 0.77-1.20]) as well as stroke (OR, 0.99 [95% CI, 0.76-1.30])

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