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All the attacks and parries, all the ornate maneuvering, crafted a conceptual filigree that I adored immediately and irreversibly and that removed me from my workaday lifeeven when, on the face of it, I was only yelling in a classroom that looked exactly like the one where I doodled through algebra or biology each week

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The Cigarette powerboat became famous when it was featured from 1984 to 1990 on the TV series Miami Vice with Don Johnson and Philip Michael Thomas.

Thus, overexpression of mdm2 inactivates both p53 and pRB in a fashion similar to some viral oncoprotein products, demonstrating a potential link between p53 and pRB in cell cycle regulation, apoptosis, and tumor progression

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