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This gradual change is evident in teens and young adults, too

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States with a high prevalence of smoking among adults also have high rates of smokers who made no attempt to change their behavior in the last year (Burns and Warner 2003), suggesting that environment plays a role in sustaining smoking behavior or promoting cessation efforts

In vitro and mouse models of e-cig exposure have found evidence of cell damage and death, increased inflammation, and impaired defenses against both viruses and bacteria (reviewed by (22))

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