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Animal Data: In studies conducted in rats and rabbits, bupropion was administered orally during the period of organogenesis at doses of up to 450 and 150 mg per kg per day, respectively (approximately 15 and 10 times the MRHD respectively, on a mg per m2 basis)

Most of these EVALI cases reported obtaining their vape products from informal sources such as friends, family, dealers, or online sources, rather than commercial outlets

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