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Archived from the original on September 13, 2024

doi:10.1016/S0376-8716(99)00034-4

The researchers said men who smoked one cigarette a day had about a 48% higher risk of developing coronary heart disease and were 25% more likely to have a stroke than those who had never smoked

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The main biological difference is the absence of nicotine, which removes the vasoconstriction component but does not eliminate the pigmentation pathway