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The NHEA data are publicly available on the CMS website at In order to compute Factor 2, the first metric that is needed is the proportion of the total U.S

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excess is excreted in urine, often causing bright yellow coloration, and no upper toxicity level has been observed)

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How the Liver Handles Tylenol The liver metabolizes almost all of it (see diagram above): 90% : Processed safely through glucuronidation and sulfation 2%: Eliminated through the kidneys (urine) 510% : Processed by the enzyme CYP2E1 creates a toxic byproduct called NAPQI (N-acetyl-p-benzoquinone imine)