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It is important to note that the observed difference between users of e-cigarettes and non-users was ~ 5%, and decreases of 1% in vascular dilation through the flow-mediated dilation test have been associated with an 8 to 11% greater risk for cardiovascular events [126]

Smoking one cigarette reduces life by 20 min According to University College, London, smoking is rapidly reducing people's life expectancy

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The reason for such structural changes in smokers may be that chronic cigarette smoking may damage microvessels and influence the blood supply to the brain [38]

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