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Smoking and schizophrenia in particular have long been recognized as tight bedfellows

The health risks, operational downtime, and inconsistent effectiveness make them impractical for frequent use

So brands used messaging around being "less irritating" or even referred to that feeling as a "cigarette hangover".When marketing to women, brands often used messaging around being more pleasant or tolerable

This takes on the classic butterfly rash shape associated with SLE

According to the TV documentary Autopsy: John Candy (via Canoe), Candy was also a regular smoker, which may have helped contribute to his declining health

However, a higher percentage of vegetable glycerin often results in slightly reduced throat hit