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People living with HIV might need larger doses of medication to suppress their symptoms than those who are HIV negative

The experience of prolonged stress, however, has a direct negative influence on our physical health, because at the same time that stress increases activity in the sympathetic division of the ANS, it also suppresses activity in the parasympathetic division of the ANS

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An exploratory aim is to examine the moderating effects of rs1799971, a polymorphism in OPRM1 , on the response to naltrexone by comparing Asn40 homozygotes with Asp40 carriers