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From many of the above mechanisms (Table 1), we observe that smoking can cause a series of injuries in the airway of asthmatics, and then through inflammatory responses (Figure 1) and/or various damage repair mechanisms (Figure 2) bring about the presence of airway remodeling characterized by more severe irreversible airflow limitation and persistent AHR

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References Agrawal A, Budney AJ, & Lynskey MT (2012)

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Risk of initiation to smoking with the use of electronic cigarettes: systematic review and meta-analysis [Article in Portuguese]

"It was a celebratory thing," he says