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6 A 2019 randomised control trial found no adverse events related to either nicotine replacement therapy (NRT) or ENDS but did find that NRT users were more likely to report nausea (37.9% versus 31.3% of ENDS users) while ENDS users were more likely to report mouth or throat irritation (65.3% versus 51.2% of NRT users)

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(2013) 15 found no significant differences in abstinence rates between those using the nicotine patch and those using e-cigarettes, while Hajek et al