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Another study using an air-liquid interface (ALI) to assess the cytotoxic effects on human bronchial epithelial cells, showed that IQOS exposure induced higher cytotoxicity (reduced metabolic activity) than e-cigarettes or air controls but lower than combustible cigarettes 22

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The study Varenicline and counseling for vaping cessation: A double-blind, randomized, parallel-group, placebo-controlled trial , shows for the first time that inclusion of varenicline in a vaping cessation program for people who use e-cigarettes and intending to quit may result in abstinence

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