METHODS Literature search A systematic search was conducted across PubMed (14 April 2024), Cochrane Library (58 April 2024), Embase (15 May 2024), and Web of Science (610 May 2024), using MeSH terms and free-text keywords related to nicotine replacement therapy, smokeless tobacco, cessation, and reduction
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Many Scottish mixtures, with added Cavendish or different Virginias, also fit well here, offering smoothness alongside complexity
Properly fermented tobacco: After curing, tobacco leaves contain high levels of chlorophyll, ammonia, and residual sugars