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Mutp53 types in cancer TP53 is located on the short arm of human chromosome 17 (17p13.1) and consists of 11 exons, 10 introns and 393 amino acid residues

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This pathological process is typically initiated by biomechanical stress or hypoxia stimuli, which induce injury and apoptosis in PAECs, ultimately compromising endothelial integrity

And I think well carry on that idea going forward