Introduction In the realm of human health, sleep is pivotal, serving not only as a period for energy storage and nervous system recuperation but also as a critical phase for reinforcing brain connections, thereby augmenting learning and memory processes ( Addressing this challenge necessitates a paradigm shift in sleep regulation strategies, focusing on the development of therapeutic agents that prioritize safety and efficacy
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IdeguchiHOhnoSTakaseKHattoriHKirinoYTakenoMet al
doi:10.1146/annurev.nutr.19.1.357
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Its characterized by: excessive hair growth (hypertrichosis), papery thin and fragile (atrophic) skin, outward turned eyelids (ectropion) and a large mouth (macrostomia)