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For most people, side effects can be managed successfully by simply rotating application sites and removing the patch at night

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Classified as a Schedule I controlled substance, cannabis remains illegal to carry across state lines, and some states have yet to implement even a medical marijuana program

A nicotine challenge to the self-medication hypothesis in a neurodevelopmental animal model of schizophrenia

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There is disagreement as to what extent cannabis might cause or worsen mental health problems and many countries have gone ahead and legalised or decriminalised cannabis use