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Competing interests The authors declare that they have no conflict of interests

This AM404 compound interacts with TRPV1 and the endocannabinoid system, directly influencing the brain's pain control pathways

Mild side effects, such as slight soreness at the injection site, may occur but typically resolve quickly

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The peptide increases VEGFR2 without increasing VEGF-A, the ligand that typically activates this receptor

Technological innovations, including point-of-care devices (208,209) and microfluidic biosensor platforms (214), lead towards rapid and user-friendly miRNA detection