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Protein oxidation also affects the acrosome reaction, which is essential for sperm-egg binding and fertilization

In addition, thalamic neurodegeneration was reported to occur independent of the detection of mutant ATXN3 immunopositive neuronal intranuclear inclusions [26]

When SLC7A11 function is impaired, intracellular GSH levels decrease, reducing GPX4 activity and increasing vulnerability to ferroptotic cell death

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Thyroid microenvironment has a high antioxidant metabolic profile at baseline due to inherently high intracellular ROS levels utilized for thyroid hormonogenesis

That literature should not be dismissed, but neither should it be promoted as if it were a body of conclusive human clinical evidence