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Inhibition of GLS-1 starting at 1 M of CB-839 was enough to reduce the mean glutathione concentration by at least 51% in both the HG-3 and MEC-1 cell lines compared to the controls

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Yonsei Med J 45(4):703710

Our kinetic study showed no inhibition by HQ in the presence of L-dopa since with rising concentrations of HQ, K m values decreased (Fig