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The sample sizes of the third and fourth groups were significantly higher than those of the first and second groups, possibly because new cigarette packaging was used in the third and fourth groups, creating a higher novelty and, consequently, a higher response rate from the participants

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Around the year 1879, to increase the appeal of their products these companies began including images on the cards which ranged from famous actresses, native american chiefs, famous sports players, flags, and wild animals

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For one organization, increasing the age to purchase tobacco products has been its sole purpose

Greater weight was given to longitudinal studies, systematic reviews, large population-based surveys, and well-controlled experimental or mechanistic studies, while evidence from cross-sectional or self-reported data was interpreted with caution