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Higher nicotine concentrations are associated with People who are dependent on nicotine may consider gradually tapering the quantity of nicotine per milliliter

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Some research supports this

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There are about 6.9 million adults in the UK who are smokers and although these figures are going down, there are still 6.9 million people who are harmfully smoking nicotine

New Engl J Med 381:17801781 Itoh M, Aoshiba K, Herai Y et al (2017) Lung injury associated with electronic cigarettes inhalation diagnosed by transbronchial lung biopsy