However, delivery across the blood-brain barrier remains a major challenge requiring innovative approaches
Patients should be made aware that it is typically a chronic disorder requiring continual and dynamic management and
Formed by tightly apposed endothelial cells supported by pericytes and astrocytic end-feet, the BBB restricts the entry of most small molecules, biologics, and nearly all gene-editing constructs [139]
NAC may cause nausea, particularly at higher doses, and has a characteristic sulphur odour that some individuals find unpleasant
Cells absorb it quickly, which is why blood levels drop fast
Third-party tested batches from an accredited outside lab (ISO 17025) carry more weight than an in-house bench checking its own work