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Nicotine salt formulations in e-liquids, which buffer pH to 5.0-5.5, enable concentrations up to 50 milligrams per milliliter without throat harshness, a breakthrough that closed the satisfaction gap with combustible cigarettes

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Additionally, since the products meet the definition of a cigarette, the FDA determined that the products are adulterated because they contain a natural or artificial characterizing flavor, or misbranded if they only purport to do so

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