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The authors found evidence of ultrastructural abnormalities in cardiomyocytes, including shrunken nuclei with chromatin condensation and fragmentation (apoptosis), nuclear malformation with extensively convoluted nuclear membranes, myofibrillar derangement, thinning and destruction, intramyocardial lipid accumulation and mitophagy, which are associated with myocardial dysfunction

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But it does mean that we can be relatively confident that switching from smoking to vaping will have health benefits

The person may have encountered some obstacles in his life and made an effort to overcome these obstacles