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The authors found about the same characteristics with respect to LODs and reproducibility

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In addition to receiving an intranasal dose of nicotine from a commercial source, the women received an injection of a radioactive tracer bound to an enzyme called aromatase, also known as estrogen synthase, which binds to estrogen

Zhao D, Aravindakshan A, Hilpert M, Olmedo P, Rule AM, Navas-Acien A, Aherrera A