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Definitions The dataset included participants information on the onset age of smoking, smoking status, age, sex, alcohol consumption, regular exercise, income, baseline comorbidities, BMI (kg/m 2 ), WC (cm), blood glucose (mg/dL), systolic blood pressure/diastolic blood pressure (SBP/DBP) (mm Hg), serum total cholesterol (mg/dL), high-density lipoprotein cholesterol (HDL-C) (mg/dL), and low-density lipoprotein cholesterol (LDL-C) (mg/dL)

As the field evolves, coupling microbial ecology with systems-level host responses may transform our understanding of tobacco-related pathogenesis

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