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In an earlier piece of work it was discovered that if a father started smoking regularly before reaching puberty, then his sons, but not daughters, had more body fat than expected

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Th-1 cells release interferon gamma (INF) and interleukin, which are IL-2, IL-12, and IL-18, while Th-2 cells release IL-4, IL-5, IL-6, IL-10, and IL-13