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PMID 31536403

Certain drugs such as the antidepressant bupropion (Zyban), the first non-nicotine-based drug for smoking cessation, can reduce cravings and mitigate the effects of withdrawal by acting at certain nicotinic receptors

Milling and refining Once sugarcane is harvested, it must be quickly processed so the sugary juice in the stalks does not ferment

72 Further, any manufacturer that has not received an MRTP order for its tobacco product may not market the product with a label, labeling, or advertising that implies the product has a reduced risk of harm or that uses the words "light," "mild," "low," or similar descriptions

For several reasons, cigarettes became the preferred tobacco product of Americans over the 20th century

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