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Elegant, timeless classics like the Cartier Tank (up to 10,000) and the Patek Philippe Calatrava (from 5000) are, says Morris, good buys, always stylish and well made with stable mechanical movements, reliable if properly maintained. Some are variable - a 1970s, gold Omega Constellation would be about 3000 while one of the unique, innovative, special project models designed for Omega by jeweller Andrew Grima would be nearer 30,000

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VMAT2 exploits this H gradient via protonmonoamine exchange to actively transport cytosolic monoamines into the vesicle against their concentration gradient, enabling vesicular storage and subsequent regulated neurotransmitter release

Kauhavan Polkka. Viola Turpeinen & John Rosendahl

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