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Moreover, a significant increase in TXB 2 levels, a metabolite of the biologically active TXA 2 , and an index of oxidative injury were reported after a single hookah smoking session [179]

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[72] While the group says it did reach the required number of signatures, it ultimately chose not to submit them because they did not know how many signatures would be eliminated in the review process, and Commissioner Piepkorn threatened to obtain the list of signers via FOIA request, which was interpreted as a political threat by the group