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Although participants generally recognized oral cancer as a serious health risk of SLT use, widespread continuation of the habit was driven by emotional dependency, social acceptance in local communities, and lack of readily accessible cessation resources

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CSE depletion resulted in the restoration of complex II and III protein levels, similar to the non-persistent effects of CSE on mitochondrial mass and Mn-SOD, while complex V levels were not significantly reduced upon CSE depletion (Figure 3F)

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The interconnected nature of nicotine addiction with other substances means that addressing smoking cessation alongside other addiction treatment creates a stronger foundation for long-term sobriety