According to the site The Spruce, The toxic dose of nicotine in pets is 1/2-1 mg per pound of pet body weight, while the lethal dose is 4 mg per pound of pet body weight
"We're all used to sore throats, but the sore throats that are reported to GPs are already unusual because it's gone outside the patient's norms." And it is the combination of persistent symptoms - sore throat, hoarseness and breathing or swallowing problems - that could be a warning sign, he said
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What is so exciting about our study is that it shows that its never too late to quit some of the people in our study had smoked more than 15,000 packs of cigarettes over their life, but within a few years of quitting many of the cells lining their airways showed no evidence of damage from tobacco. Smoking causes up to 10,000 extra mutations in nine out of every 10 lung cells, the researchers found, including many that cause cancer