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Cigarette Excise Tax State cigarette tax: $2.87 per pack of 20 (set by Proposition 56 in 2016, effective April 1, 2017) Federal cigarette tax: approximately $1.01 per pack of 20 (under Internal Revenue Code section 5701) Total tax burden on a pack of cigarettes in California: nearly $4.00 before sales tax Other Tobacco Products (OTP) Tax The CDTFA recalculates the OTP tax rate every year on April 1, based on cigarette wholesale price changes

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The levels of tobacco exposure-related biomarkers were improved following HTP use, compared to smoking CSs

Mouse NLRP1B was identified in a genetic screen as a determinant of differential susceptibility between mouse strains to Lethal Toxin, a virulence factor responsible for the major pathologies seen during infection by the bacterial pathogen Bacillus anthracis (107)