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Using isolated rat aorta, the researchers demonstrated that BPC 157 induced a concentration-dependent vasodilation that was endothelium-dependent and mediated by nitric oxide (NO)

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Lab Invest 81 , 645672 (2001)

We first studied hyperpolarized [1- 13 C]dehydroascorbate in the normal rat brain, demonstrating its robust conversion to [1- 13 C]vitamin C, consistent with rapid transport of the oxidized form across the blood-brain barrier