The relative risk of all-cause mortality due to SLT use is also higher among women.[9] Several studies have shown that women have difficulty in quitting tobacco, tend to experience faster relapse due to stressful events or depression and fail to maintain long-term abstinence.[10,11,12] Evidence suggests that estrogen may enhance nicotine metabolism in women, which can affect their ability to quit tobacco successfully.[13] Since its introduction in the 17 th century in India, tobacco chewing was believed to have calming and stimulating qualities and was not only socially acceptable but also a part of its culture.[14] SLT use can be found in other South and Southeast Asian countries as well
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First, a univariate analysis was performed using the t-test and 2 -test to comparatively analyze the differences between the characteristics of participants between smoking relapsers and abstinent smokers, and a survival curve was generated using the Kaplan-Meier method to examine the patterns of smoking relapse according to the duration of smoking abstinence
Reductions in tobacco consumption resulting from utilization of tobacco cessation services will result in a decline in tobacco-related sickness and death