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Further studies are needed to assess the frequency of such mutations among patients and explore ways to inhibit its activity and restore sensitivity to hormonal therapy [51]

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The carnitine bound OCTN2-occluded structure defines the substrate and sodium ion binding sites In the presence of 10 mM l-carnitine the structure of OCTN2 was determined in the fully occluded, carnitine- and Na + -bound conformation (Fig

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Sleator RD, Francis GA, O'Beirne D, Gahan CG, Hill C: Betaine and carnitine uptake systems in Listeria monocytogenes affect growth and survival in foods and during infection

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