Plasma selenium-dependent glutathione peroxidase
147 Overexpression of miR-144-3p could downregulate the GSH/GSSG ratio, increase the levels of ROS, Fe 2+ , and ACSL4, promote ferroptosis and thus reduce the metastasis of osteosarcoma cells, while high expression of ZIB1 plays the opposite role, 147 indicating that miR-144-3p and its downstream ZIB1 are involved in the development and metastasis of osteosarcoma mainly by interfering with iron metabolism and redox homeostasis
Formononetin upregulates Nrf2/HO-1 signaling and prevents oxidative stress, inflammation, and kidney injury in methotrexate-induced rats
With aging, mitochondrial electron transport chain function gradually diminishes, leading to a decrease in ATP production efficiency
Li Z-S, Zhao Y, Rea PA 1995 Magnesium adenosine 5'-triphosphate-energized transport of glutathione-S-conjugates by plant vacuolar membrane vesicles
Fumarate Hydratase Inactivation in Hereditary Leiomyomatosis and Renal Cell Cancer Is Synthetic Lethal with Ferroptosis Induction