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They are urging the FDA to strengthen the enforcement of "illegal" synthetic nicotine e-cigarettes in the American e-cigarette market, as these illegal products are estimated to account for about half of the overall e-cigarette market share

Therefore, it is concerning that between 2016 and 2018, more than 21 million people in the United States were exposed year-round to unhealthy levels of particle pollution (256)

A great example of this is a randomized controlled trial from 2019 comparing nicotine replacement to e-cigarettes for smoking cessation

Artificial sweeteners have been linked to an increased risk of heart attack, stroke, and diabetes