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Furthermore, the use of 6-hydroxydopamine and rotenone induced the translocation of cardiolipin to the OMM in neuronal cells, promoting the binding of LC3 to cardiolipin and the occurrence of mitophagy ( 3 Interactions between mitophagy and fibrotic processes Fibrosis is a pathological remodeling caused by an excessive tissue repair response (Wynn, 2008

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PNE was found to alter norepinephrine transporter (NET) binding expression in both sexes and Catechol-O-methyl transferase (COMT)-dependent dopamine turnover in males

Benefits : Complex : Smoky tobacco and fresh notes combined for bold and refreshing flavour