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Although antibiotics are generally effective against bacterial pneumonia, current treatment approaches remain insufficient due to several barriers, including the lungs unique mucus barrier, low pH, high oxidative stress, disruption of alveolar surfactants, and accumulation of hypertonic fluid on the airway surface

showed reduced proportions of CD4 + and CD8 + lymphocytes in the spleen of mice due to L-carnitine supplementation ( + and CD8 + lymphocyte counts than non-survivors, suggesting a beneficial effect on health of lower levels of these cell populations during periods of immune challenge

Many commercial formulations are stable at room temperature

Clinical trials provide additional details

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