The researchers explain that smaller packs might reduce consumption because it takes effort to buy or open a new pack, or because people tend to consume a specific number of units in a pre-specified period of time
Although several carcinogens were already known at the time (for example, benzo[a]pyrene was isolated from coal tar and demonstrated to be a potent carcinogen in 1933), none were known to be contained in adequate quantities in tobacco smoke
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According to Americans for Safe Access, a person would need to smoke the equivalent of 1,500 pounds of cannabis in 15 minutes to overdose
Regulatory toxicology and pharmacology : RTP , 71(1), 2434