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This long-term decline points to the positive impact of anti-smoking campaigns and tobacco control measures

Direct cellular effects of ETS on epithelial cells results in increased permeability, mucus overproduction, impaired mucociliary clearance, increased release of proinflammatory cytokines and chemokines, enhanced recruitment of macrophages and neutrophils and disturbed lymphocyte balance towards Th2

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A 2022 review published in The BMJ discussed the impact of vaping on respiratory health, noting associations with acute lung injury and potential long-term effects on lung function