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DSM-5, Diagnostic and statistical manual, 5 th revision

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therefore, we addressed this variability by analysing extreme scenarios based on the upper- and lower-bound life expectancy for smokers and non-smokers which thereby take into account the worst and best-case scenarios respectively (computed based on GBDs all-cause mortalitys upper-bound and lower bound values) as shown in Tables 1 and 2

Rather than focusing exclusively on health harms, participants recommended engaging adolescents in balanced discussions about what is gained or lost through smoking and non-smoking