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A systematic review of 13 randomized controlled trials sought to find out if pre-surgery smoking cessation treatments are effective in the short and long term, and if they result in fewer complications

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However, the country-specific (Sweden) relative risk for ischaemic heart disease (RR 0.94, 95% CI 0.871.03) and both country-specific (RR 1.02, 95% CI 0.931.13 [Sweden]) and non-specific relative risks for stroke (RR 1.03, 95% CI 0.941.14) remained statistically insignificant

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Here, similar findings were observed in the nicotine-exposed testicular tissue, leading to hypoxia and compensatory mitochondrial dysfunction

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