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The role of the refill or tank is to hold the heating element and the e-liquid

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Biosci Rep 32:115 Schaller J-P, Keller D, Poget L, Pratte P, Kaelin E, McHugh D, Cudazzo G, Smart D, Tricker AR, Gautier L, Yerly M, Pires RR, Le Bouhellec S, Ghosh D, Hofer I, Garcia E, Vanscheeuwijck P, Maeder S (2016) Evaluation of the tobacco heating system 2.2 part 2: chemical composition, genotoxicity, cytotoxicity, and physical properties of the aerosol

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